SCHEMBL1594728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19396263	0.85	ALDH1A1 (0.43)	ALDH1A1HPGDYEATS4POLBCDK4
	SCHEMBL1594309	0.84	CDK4 (0.38)	ALDH1A1HPGDYEATS4POLBCDK4
	SCHEMBL1593562	0.83	YEATS4 (0.45)	ALDH1A1HPGDYEATS4POLBCDK4
	SCHEMBL1594608	0.79	YEATS4 (0.42)	ALDH1A1HPGDYEATS4POLBLMNA
	SCHEMBL1593939	0.78	ALDH1A1 (0.41)	ALDH1A1HPGDYEATS4POLBCDK4
	SCHEMBL19396265	0.74	ALDH1A1 (0.43)	ALDH1A1HPGDYEATS4POLBLMNA
	SCHEMBL19396266	0.72	HPGD (0.47)	ALDH1A1HPGDYEATS4POLBCDK4
	SCHEMBL1594691	0.72	SMN1; SMN2 (0.44)	ALDH1A1HPGDYEATS4POLBLMNA
	SCHEMBL9966107	0.72	SMN1; SMN2 (0.44)	ALDH1A1HPGDYEATS4POLBLMNA
	SCHEMBL19396262	0.71	LIPE (0.42)	ALDH1A1HPGDYEATS4POLBCDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.