Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 4/20 | 0.39 |
| ▸ | CCND1 | P24385 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594728 | 0.85 | ALDH1A1 (0.38) | ALDH1A1HPGDYEATS4POLBCDK4 | |
| SCHEMBL19396266 | 0.84 | HPGD (0.47) | ALDH1A1HPGDYEATS4POLBCDK4 | |
| SCHEMBL19396262 | 0.83 | LIPE (0.42) | ALDH1A1HPGDYEATS4POLBCDK4 | |
| SCHEMBL19396265 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDYEATS4POLBLMNA | |
| SCHEMBL1594608 | 0.76 | YEATS4 (0.42) | ALDH1A1HPGDYEATS4POLBLMNA | |
| SCHEMBL1593562 | 0.75 | YEATS4 (0.45) | ALDH1A1HPGDYEATS4POLBCDK4 | |
| SCHEMBL19396260 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HPGDYEATS4POLBLMNA | |
| SCHEMBL1594309 | 0.71 | CDK4 (0.38) | ALDH1A1HPGDYEATS4POLBCDK4 | |
| SCHEMBL19396267 | 0.69 | HPGD (0.46) | ALDH1A1HPGDYEATS4POLBLMNA | |
| SCHEMBL19396270 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HPGDYEATS4POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273968-A1 | MAO-B INHIBITORS AND REHABILITATION | DART NEUROSCIENCE, LLC | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273968-A1 | MAO-B INHIBITORS AND REHABILITATION | MAOB, MAOA, HTR2B | ALDH1A1 1300/4885HPGD 932/4885YEATS4 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.