Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804924 | 0.79 | HSD17B10 (0.44) | ALDH1A1CYP3A4TDP1HPGDALOX15 | |
| SCHEMBL9182158 | 0.78 | VCAM1 (0.47) | PLK1ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL1024025 | 0.76 | CYP3A4 (0.66) | GPR35PLK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL1025631 | 0.74 | MAPK1 (0.51) | GPR35PLK1ALDH1A1CYP3A4HPGD | |
| SCHEMBL103341 | 0.73 | GPR35 (0.65) | GPR35ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL310420 | 0.72 | GPR35 (0.69) | GPR35ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL15947450 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1HPGDALOX15 | |
| SCHEMBL2165473 | 0.71 | GPR35 (1.00) | GPR35ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL30807397 | 0.71 | GPR35 (1.00) | GPR35ALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL7751651 | 0.70 | ALDH1A1 (0.53) | PLK1ALDH1A1CYP3A4TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955178-A1 | CONDENSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-12-16 | — | — | EP | disclosed |
| WO-2014123205-A1 | CONDENSED HETEROCYCLIC COMPOUND | 住友化学株式会社 (JP) | 2014-08-14 | — | — | WO | disclosed |