Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613974 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL25613807 | 0.91 | ICAM1 (0.36) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL7388980 | 0.74 | TRPA1 (0.42) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL5063041 | 0.74 | CYP3A4 (0.47) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL4640526 | 0.72 | CA12 (0.46) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL31525804 | 0.70 | CA2 (0.41) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL7783619 | 0.69 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL14086672 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL7368433 | 0.68 | KYAT1 (0.51) | ALDH1A1MAPTCYP19A1MAOBCA2 | |
| SCHEMBL30373725 | 0.68 | ALDH1A1 (0.45) | ALDH1A1MAPTCYP19A1MAOBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014124072-A2 | COUMARIN-FUNCTIONALIZED POLYOLEFIN AND ASSOCIATED CYCLODIMERIZATION PRODUCTS, PREPARATION METHODS, AND ELECTRONIC DEVICES | UNIVERSITY OF MASSACHUSETTS (US) | 2014-08-14 | — | — | WO | disclosed |