Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263058 | 1.00 | PDK1 (0.33) | PDK1ALDH1A1CA2HPGDCA1 | |
| SCHEMBL12148923 | 1.00 | PDK1 (0.33) | PDK1ALDH1A1CA2HPGDCA1 | |
| SCHEMBL21418765 | 1.00 | PDK1 (0.33) | PDK1ALDH1A1CA2HPGDCA1 | |
| SCHEMBL10120755 | 1.00 | PDK1 (0.33) | PDK1ALDH1A1CA2HPGDCA1 | |
| SCHEMBL2582358 | 0.85 | PGD (0.33) | ALDH1A1HPGDPGD | |
| SCHEMBL7240708 | 0.85 | PGD (0.33) | ALDH1A1HPGDPGD | |
| SCHEMBL8074120 | 0.80 | PDK1 (0.40) | PDK1ALDH1A1CA2CA1CA9 | |
| SCHEMBL23679585 | 0.79 | CA2 (0.39) | PDK1ALDH1A1CA2CA1CA9 | |
| SCHEMBL7257546 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGD | |
| SCHEMBL13675166 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015038596-A1 | NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |