Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381957 | 0.70 | — | — | |
| SCHEMBL7101928 | 0.70 | — | — | |
| SCHEMBL29039601 | 0.68 | — | — | |
| SCHEMBL1699087 | 0.67 | — | — | |
| SCHEMBL8626789 | 0.67 | — | — | |
| SCHEMBL6480442 | 0.66 | DUT (0.31) | — | |
| SCHEMBL336315 | 0.65 | — | — | |
| SCHEMBL4469415 | 0.62 | — | — | |
| SCHEMBL5613275 | 0.62 | — | — | |
| SCHEMBL8520644 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220085-B1 | FLUOROALKYL TETRABENAZINE CARBINOL COMPOUNDS AS IMAGING AGENTS AND PROBES | GEN ELECTRIC (US) | 2014-02-12 | — | — | EP | disclosed |
| US-8013161-B1 | Fluoroalkyl tetrabenazine carbinol compounds as imaging agents and probes | GENERAL ELECTRIC COMPANY (US) | 2011-09-06 | — | — | US | disclosed |
| US-20110206609-A1 | FLUOROALKYL TETRABENAZINE CARBINOL COMPOUNDS AS IMAGING AGENTS AND PROBES | GENERAL ELECTRIC COMPANY (US) | 2011-08-25 | — | — | US | disclosed |
| US-7919622-B2 | Intermediates for fluorinated tetrabenazine carbinol compounds imaging agents and probes | GENERAL ELECTRIC COMPANY | 2011-04-05 | — | — | US | disclosed |
| US-20090149654-A1 | INTERMEDIATES FOR FLUORINATED TETRABENAZINE CARBINOL COMPOUNDS IMAGING AGENTS AND PROBES | GENERAL ELECTRIC COMPANY (US) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206609-A1 | FLUOROALKYL TETRABENAZINE CARBINOL COMPOUNDS AS IMAGING AGENTS AND PROBES | SOAT2, SOAT1, CPT2 | APLNR 903/4885 |
| US-20090149654-A1 | INTERMEDIATES FOR FLUORINATED TETRABENAZINE CARBINOL COMPOUNDS IMAGING AGENTS AND PROBES | RHOT2, CPT2, HHAT | APLNR 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.