SCHEMBL15949797

SCHEMBL15949797

c1cncc(-c2ccc(-n3nc4ccc(-c5c6ccccc6c(-c6cccc7ccccc67)c6ccccc56)cc4n3)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
KDM4E B2RXH2 4/20 0.41
RAB9A P51151 4/20 0.41
HPGD P15428 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP11B1 P15538 2/20 0.40
DHODH Q02127 2/20 0.39
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP11B2 P19099 1/20 0.39
GPR84 Q9NQS5 1/20 0.37
NPC1 O15118 3/20 0.37
MAPK1 P28482 1/20 0.37
BCHE P06276 1/20 0.37
CYP2A6 P11509 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
APAF1 O14727 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30911070 1.00 ALDH1A1 (0.41) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL17805196 0.96 MAPT (0.41) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL30911071 0.95 MAPT (0.41) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL15950391 0.95 MAPT (0.41) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL15949855 0.93 GRM5 (0.41) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL30911061 0.93 GRM5 (0.41) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL16355313 0.89 MAPT (0.39) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL15949791 0.88 CYP11B2 (0.53) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL30911067 0.88 CYP11B2 (0.53) ALDH1A1MAPTKDM4ERAB9AHPGD
SCHEMBL15949761 0.88 NPC1 (0.44) ALDH1A1MAPTKDM4ERAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2767534-B1 NEW BENZOTRIAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IN WHICH SAID DERIVATIVE IS USED HODOGAYA CHEMICAL CO LTD (JP) 2020-06-03 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed
EP-2767534-A1 NEW BENZOTRIAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IN WHICH SAID DERIVATIVE IS USED Hodogaya Chemical Co., Ltd. (JP) 2014-08-20 EP disclosed
EP-2767534-A1 NEW BENZOTRIAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IN WHICH SAID DERIVATIVE IS USED Hodogaya Chemical Co., Ltd. (JP) 2014-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 ALDH1A1 228/4885MAPT 2734/4885KDM4E 1822/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 ALDH1A1 228/4885MAPT 2734/4885KDM4E 1822/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT ALDH1A1 599/4885MAPT 2246/4885KDM4E 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.