Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296142 | 0.85 | BCAT2 (0.49) | BCAT2AOC3LMNAGRM2GRM3 | |
| SCHEMBL15006719 | 0.77 | RIPK1 (0.52) | BCAT2AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL3746491 | 0.76 | RIPK1 (0.55) | BCAT2AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL8027464 | 0.76 | RIPK1 (0.55) | BCAT2AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL13507144 | 0.74 | KDM4E (0.60) | BCAT2AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL15958712 | 0.74 | AOC3 (0.47) | BCAT2AOC3LMNAKDM4EL3MBTL1 | |
| SCHEMBL12435669 | 0.71 | RIPK1 (0.64) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL5163930 | 0.71 | RIPK1 (0.64) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL13003036 | 0.71 | RIPK1 (0.64) | AOC3LMNAKDM4EL3MBTL1RIPK1 | |
| SCHEMBL28787515 | 0.71 | LMNA (0.52) | BCAT2AOC3LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725636-A1 | HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM | FHJ SCIENTIFIC, INC. (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995010272-A1 | HYDROXYL IONS AS UNIQUE THERAPEUTIC AGENTS AND COMPOUNDS THAT MODULATE THESE IONS, COMPOSITIONS EMPLOYING THESE AGENTS, THERAPEUTIC METHODS FOR USING SUCH AGENTS AND PROCESSES FOR PREPARING THEM | FHJ SCIENTIFIC, INC. (US) | 1995-04-20 | — | — | WO | disclosed |