SCHEMBL1595970

SCHEMBL1595970

O=S(=O)(Cl)c1ccc(CCl)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KMT2A Q03164 2/20 0.32
TSHR P16473 1/20 0.32
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
FABP4 P15090 2/20 0.31
PLCG1 P19174 1/20 0.31
MEN1 O00255 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
AURKA O14965 1/20 0.30
AURKB Q96GD4 1/20 0.30
TRPV4 Q9HBA0 2/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642257 0.85 LDHA (0.36) LDHAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL9165551 0.83 ALDH1A1 (0.48) LDHAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL17212138 0.83 TTR (0.46) LDHAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL314045 0.80 LDHA (0.33) LDHAALDH1A1HSD17B10TDP1
SCHEMBL2466440 0.78 L3MBTL1 (0.44) ALDH1A1HSD17B10TDP1KMT2ATSHR
SCHEMBL29558862 0.78 L3MBTL1 (0.44) ALDH1A1HSD17B10TDP1KMT2ATSHR
SCHEMBL2385214 0.76 RXFP1 (0.46) LDHAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL30987398 0.76 RXFP1 (0.46) LDHAALDH1A1HSD17B10TDP1KMT2A
SCHEMBL10641975 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10TDP1KMT2ATSHR
SCHEMBL1338882 0.74 CASP3 (0.46) ALDH1A1HSD17B10KMT2ATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1780224-B1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2015-02-18 EP disclosed
US-8710165-B2 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
US-20110152388-A1 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2011-06-23 US disclosed
US-7919570-B2 narrowly dispersed; controlled molecular weight; ionic conductivity, shape stability; battery adhesive or binder; 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane or pentaerythritol reacted with bromoisobutyroyl bromide for core; living radical polymerization of acrylate or a styrene at halogen atoms as the arms NIPPON SODA CO., LTD. (JP) 2011-04-05 US disclosed
US-20080214685-A1 Multibrached Polymer and Method for Producing the Same NIPPON SODA CO., LTD. (JP) 2008-09-04 US disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed