Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595970 | 0.85 | LDHA (0.36) | LDHAALDH1A1TDP1HSD17B10POLB | |
| SCHEMBL9165551 | 0.83 | ALDH1A1 (0.48) | LDHAALDH1A1TDP1HSD17B10POLB | |
| SCHEMBL7791002 | 0.81 | TTR (0.47) | LDHAALDH1A1HSD17B10CYP1A2HIF1A | |
| SCHEMBL314045 | 0.80 | LDHA (0.33) | LDHAALDH1A1TDP1HSD17B10 | |
| SCHEMBL7020846 | 0.79 | THRB (0.42) | LDHAALDH1A1HSD17B10CTSBHTT | |
| SCHEMBL7020849 | 0.79 | TTR (0.46) | LDHAALDH1A1HSD17B10CYP1A2HIF1A | |
| SCHEMBL30537735 | 0.78 | GABRA1 (0.43) | ALDH1A1HTTCNR2CYP1A2 | |
| SCHEMBL5682891 | 0.78 | GABRA1 (0.43) | ALDH1A1HTTCNR2CYP1A2 | |
| SCHEMBL29352142 | 0.77 | CNR2 (0.39) | ALDH1A1LMNACNR2L3MBTL1 | |
| SCHEMBL22116822 | 0.76 | COMT (0.50) | ALDH1A1TDP1HSD17B10POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678196-B1 | SULFONYLAMINO-PEPTIDOMIMETICS ACTIVE ON THE SOMATOSTATIN RECEPTOR SUBTYPES 4 (SSTR4) AND 1 (SSTR1) | WURSTER SIEGFRIED (FI) | 2008-08-13 | — | — | EP | disclosed |
| US-20070129313-A1 | Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1) | SIEGFRIED WURSTER (FI) | 2007-06-07 | — | — | US | disclosed |
| EP-1678196-A1 | SULFONYLAMINO-PEPTIDOMIMETICS ACTIVE ON THE SOMATOSTATIN RECEPTOR SUBTYPES 4 (SSTR4) AND 1 (SSTR1) | Oy Juvantia Pharma Ltd (FI) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005033124-A1 | SULFONYLAMINO-PEPTIDOMIMETICS ACTIVE ON THE SOMATOSTATIN RECEPTOR SUBTYPES 4 (SSTR4) AND 1 (SSTR1) | OY JUVANTIA PHARMA LTD (FI) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129313-A1 | Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1) | SSTR4, SSTR1, SSTR3 | LDHA 4656/4885ALDH1A1 2722/4885TDP1 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.