SCHEMBL15964263

SCHEMBL15964263

CCn1c2ccccc2c2ccc3c(c4ccccc4n3C)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.50
MAPT P10636 5/20 0.46
KDM4E B2RXH2 5/20 0.46
HTT P42858 4/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HBB P68871 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208662 0.89 KDM4E (0.54) MAPTKDM4EHTTALDH1A1HPGD
SCHEMBL19769380 0.88 GPR3 (0.39) GPR3MAPTKDM4EHTTALDH1A1
SCHEMBL15964274 0.88 KDM4E (0.50) GPR3MAPTKDM4EHTTALDH1A1
SCHEMBL19769373 0.86 CYP1A2 (0.55) MAPTKDM4EHTTALDH1A1HPGD
SCHEMBL19769372 0.86 HPGD (0.46) GPR3MAPTKDM4EHTTALDH1A1
SCHEMBL19769430 0.86 TP53 (0.49) MAPTKDM4EHTTALDH1A1HPGD
SCHEMBL15964285 0.83 ALKBH5 (0.53) GPR3MAPTKDM4EHTTALDH1A1
SCHEMBL15964265 0.83 ALDH1A1 (0.55) GPR3MAPTKDM4EHTTALDH1A1
SCHEMBL2741407 0.83 GPR3 (0.61) GPR3MAPTKDM4EHTTALDH1A1
SCHEMBL19769914 0.83 GPR3 (0.42) GPR3MAPTKDM4EHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142222-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-11 US disclosed
US-20230128732-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20160293853-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20160168162-A1 LUMINESCENT COMPOUND AND ELECTROLUMINESCENT DEVICE EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-16 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168162-A1 LUMINESCENT COMPOUND AND ELECTROLUMINESCENT DEVICE EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE OCIAD2, OCIAD1, JUND GPR3 1532/4885MAPT 229/4885KDM4E 2598/4885
US-20160293853-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND GPR3 3529/4885MAPT 2802/4885KDM4E 666/4885
US-20230142222-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, CTNNA1, CCNT1 GPR3 1051/4885MAPT 2809/4885KDM4E 2601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.