SCHEMBL15964274

SCHEMBL15964274

CCn1c2ccccc2c2c3c(ccc21)c1ccccc1n3C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
MAPT P10636 5/20 0.50
MAPK1 P28482 4/20 0.50
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
HTT P42858 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
HPGD P15428 2/20 0.50
HBB P68871 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.47
FTO Q9C0B1 1/20 0.47
GPR3 P46089 1/20 0.46
NPC1 O15118 1/20 0.45
GAA P10253 1/20 0.45
RAB9A P51151 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208662 0.89 KDM4E (0.54) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL15964263 0.88 GPR3 (0.50) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL26329739 0.84 CYP1A2 (0.53) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL15964265 0.83 ALDH1A1 (0.55) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL15964285 0.83 ALKBH5 (0.53) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL2741407 0.83 GPR3 (0.61) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL18120397 0.83 KDM4E (0.49) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL19769373 0.83 CYP1A2 (0.55) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL16978834 0.81 ALDH1A1 (0.64) KDM4EMAPTMAPK1ALDH1A1MEN1
SCHEMBL21304017 0.81 PGR (0.50) KDM4EMAPTMAPK1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142222-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-11 US disclosed
US-20230128732-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-9716238-B2 Boron compound for organic electroluminescent elements, and organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2017-07-25 US disclosed
US-20160293853-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20160020397-A1 BORON COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-01-21 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160020397-A1 BORON COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT EBPL, CDYL, L3MBTL3 KDM4E 567/4885MAPT 1182/4885MAPK1 2388/4885
US-20160293853-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND KDM4E 666/4885MAPT 2802/4885MAPK1 3755/4885
US-20230142222-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, CTNNA1, CCNT1 KDM4E 2601/4885MAPT 2809/4885MAPK1 385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.