Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650947 | 0.91 | HIF1A (0.54) | HIF1AEPAS1CYP1A2LMNAAGTR1 | |
| SCHEMBL15954055 | 0.89 | HIF1A (0.69) | HIF1AEPAS1CYP1A2LMNAAGTR1 | |
| SCHEMBL31425001 | 0.89 | HIF1A (0.69) | HIF1AEPAS1CYP1A2LMNAAGTR1 | |
| SCHEMBL15965412 | 0.85 | HIF1A (0.45) | HIF1AEPAS1CYP1A2LMNASLC6A4 | |
| SCHEMBL17967102 | 0.84 | HIF1A (0.63) | HIF1AEPAS1CYP1A2LMNAAGTR1 | |
| SCHEMBL17997949 | 0.84 | HIF1A (0.63) | HIF1AEPAS1CYP1A2LMNAAGTR1 | |
| SCHEMBL21103198 | 0.82 | TSHR (0.63) | HIF1AEPAS1CYP1A2LMNAAGTR1 | |
| SCHEMBL12300385 | 0.82 | HIF1A (0.89) | HIF1AEPAS1 | |
| SCHEMBL12300413 | 0.81 | HIF1A (0.84) | HIF1AEPAS1 | |
| SCHEMBL15954437 | 0.81 | LMNA (0.62) | HIF1AEPAS1CYP1A2LMNAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359391-B2 | Selective C—O bond cleavage of oxidized lignin and lignin-type materials into simple aromatic compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-06-07 | — | — | US | disclosed |
| US-20150259368-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-09-17 | — | — | US | disclosed |
| US-8969534-B2 | Selective aerobic alcohol oxidation method for conversion of lignin into simple aromatic compounds | Wisconsin Alumni Research Foundataion (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140235838-A1 | SELECTIVE AEROBIC ALCOHOL OXIDATION METHOD FOR CONVERSION OF LIGNIN INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259368-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | AOC2, AOX1, AOC3 | HIF1A 2943/4885EPAS1 3613/4885CYP1A2 477/4885 |
| US-20140235838-A1 | SELECTIVE AEROBIC ALCOHOL OXIDATION METHOD FOR CONVERSION OF LIGNIN INTO SIMPLE AROMATIC COMPOUNDS | AOX1, SOD1, NOX4 | HIF1A 1336/4885EPAS1 1982/4885CYP1A2 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.