Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073549 | 0.86 | FOLH1 (0.44) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL18882588 | 0.86 | FOLH1 (0.44) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL5023570 | 0.84 | FOLH1 (0.50) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL17050165 | 0.84 | SIRT6 (0.50) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL5023568 | 0.84 | FOLH1 (0.50) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL13783657 | 0.83 | SIRT6 (0.39) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL13783659 | 0.83 | SIRT6 (0.42) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL17304948 | 0.80 | SIRT6 (0.42) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL20978516 | 0.80 | SIRT6 (0.42) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL14878853 | 0.80 | SIRT6 (0.42) | SIRT6SIRT1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260580-A1 | GENETIC DETECTION PLATFORM | PHARMOZYME, INC. | 2017-09-14 | — | — | US | disclosed |
| US-20140235555-A1 | Pharmaceutical compositions comprising polyethylene glycol having a molecular weight of less than 600 daltons | NOVARTIS AG (CH) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260580-A1 | GENETIC DETECTION PLATFORM | POLN, POLI, POLRMT | SIRT6 4307/4885SIRT1 4846/4885GNAI3 435/4885 |
| US-20140235555-A1 | Pharmaceutical compositions comprising polyethylene glycol having a molecular weight of less than 600 daltons | PGM2, PLG, RPL7 | SIRT6 2404/4885SIRT1 2344/4885GNAI3 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.