SCHEMBL5023568

SCHEMBL5023568

CCCNC(CCCCN)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.50
▸ SLC6A5 Q9Y345 1/20 0.49
▸ GGT1 P19440 1/20 0.49
▸ TLR2 O60603 2/20 0.48
▸ SIRT6 Q8N6T7 1/20 0.47
▸ SIRT1 Q96EB6 1/20 0.47
▸ GSR P00390 1/20 0.46
▸ NOD1 Q9Y239 2/20 0.45
▸ RNPEP Q9H4A4 1/20 0.44
▸ GNAI3 P08754 1/20 0.44
▸ GNAO1 P09471 1/20 0.44
▸ GNAI1 P63096 1/20 0.44
▸ MMP2 P08253 1/20 0.41
▸ MMP9 P14780 1/20 0.41
▸ CPB2 Q96IY4 7/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023570 1.00 FOLH1 (0.50) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL29233125 0.92 FOLH1 (0.44) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL8751938 0.91 SLC6A5 (0.55) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL8751936 0.91 SLC6A5 (0.55) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL367557 0.90 NOD1 (0.56) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL367558 0.90 NOD1 (0.56) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL2050730 0.88 NOD1 (0.58) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL9791228 0.88 NOD1 (0.58) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL199411 0.88 NOD1 (0.58) FOLH1SLC6A5GGT1TLR2SIRT6
SCHEMBL31050906 0.88 NOD1 (0.58) FOLH1SLC6A5GGT1TLR2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346901-A1 MEANS AND METHODS FOR PREPARING ENGINEERED PROTEINS BY GENETIC CODE EXPANSION IN INSECT CELLS EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2018-12-06 — — US disclosed
EP-3384021-A1 MEANS AND METHODS FOR PREPARING ENGINEERED PROTEINS BY GENETIC CODE EXPANSION IN INSECT CELLS European Molecular Biology Laboratory (DE) 2018-10-10 — — EP disclosed
WO-2017093254-A1 MEANS AND METHODS FOR PREPARING ENGINEERED PROTEINS BY GENETIC CODE EXPANSION IN INSECT CELLS EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2017-06-08 — — WO disclosed
US-20080188079-A1 METAL-POLISHING COMPOSITION AND CHEMICAL MECHANICAL POLISHING METHOD BY USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20060263342-A1 Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2006-11-23 — — US disclosed
US-5614510-A AMMONIUM SALTS PERSTORP AB (SE) 1997-03-25 — — US disclosed
EP-0627922-A1 A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY OF INOSITOL PHOSPHATE PERSTORP AB (SE) 1994-12-14 — — EP disclosed
WO-1993016705-A1 A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY OF INOSITOL PHOSPHATE PERSTORP AB (SE) 1993-09-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180346901-A1 MEANS AND METHODS FOR PREPARING ENGINEERED PROTEINS BY GENETIC CODE EXPANSION IN INSECT CELLS IARS1, OSGEP, NSUN3 FOLH1 364/4885SLC6A5 568/4885GGT1 623/4885
US-20060263342-A1 Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines SPAG5, NASP, TMEM120A FOLH1 243/4885SLC6A5 2960/4885GGT1 1756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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