Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23888701 | 0.81 | DNMT3B (0.44) | DNMT3BPOLBKDM4EMEN1KMT2A | |
| SCHEMBL5727686 | 0.81 | AR (0.62) | DNMT3BKDM4EMAPTHSD17B10 | |
| SCHEMBL1021883 | 0.80 | MEN1 (0.44) | DNMT3BKDM4EMEN1KMT2AMAPT | |
| SCHEMBL30844063 | 0.80 | MEN1 (0.44) | DNMT3BKDM4EMEN1KMT2AMAPT | |
| SCHEMBL16464306 | 0.79 | DNMT3B (0.42) | DNMT3BPOLBKDM4EMEN1KMT2A | |
| SCHEMBL10545611 | 0.78 | TP53 (0.43) | DNMT3BPOLBKDM4EMEN1KMT2A | |
| SCHEMBL27353671 | 0.77 | TP53 (0.49) | DNMT3BKDM4EMEN1KMT2AMAPT | |
| SCHEMBL5486010 | 0.75 | HTT (0.44) | DNMT3BKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4365498 | 0.74 | AR (0.70) | KDM4EMEN1KMT2AMAPTGAA | |
| SCHEMBL14881366 | 0.74 | GRIN2D (0.40) | MEN1KMT2AGAATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925251-B2 | Treatments for Mycobacterium tuberculosis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-03-27 | — | — | US | disclosed |
| US-20140243255-A1 | TREATMENTS FOR MYCOBACTERIUM TUBERCULOSIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243255-A1 | TREATMENTS FOR MYCOBACTERIUM TUBERCULOSIS | CLPP, LONP1, CLPX | DNMT3B 3528/4885POLB 927/4885KDM4E 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.