Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KLK3 | P07288 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159319 | 0.83 | MAOA (0.52) | TSHRCYP3A4KDM4EPKMALDH1A1 | |
| SCHEMBL29809325 | 0.83 | MAOA (0.52) | TSHRCYP3A4KDM4EPKMALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28719469 | 0.82 | TSHR (0.47) | TSHRCYP3A4ALDH1A1MAPTKMT2A | |
| SCHEMBL3870999 | 0.81 | ACHE (0.48) | TSHRCYP3A4KDM4EPKMALDH1A1 | |
| SCHEMBL12517268 | 0.81 | S100A4 (0.54) | CYP3A4KDM4EPKMALDH1A1MAPT | |
| SCHEMBL842415 | 0.80 | KMT2A (0.47) | TSHRCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL21632211 | 0.80 | CYP3A4 (0.50) | TSHRCYP3A4KDM4EPKMALDH1A1 | |
| SCHEMBL2047715 | 0.77 | MAPT (0.49) | TSHRCYP3A4ALDH1A1MAPTKMT2A | |
| SCHEMBL27943843 | 0.75 | TDP1 (0.52) | TSHRKDM4EPKMALDH1A1MAPT | |
| SCHEMBL20291524 | 0.75 | CYP3A4 (0.61) | TSHRCYP3A4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873694-B2 | Imidazole quinoline-based immune system modulators | JANUS BIOTHERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20140242121-A1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140242121-A1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | IRF3, HLA-DRB1, IFNG | TSHR 2685/4885CYP3A4 777/4885KDM4E 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.