SCHEMBL2199161

SCHEMBL2199161

O=S(=O)(c1cccc(Cl)c1)c1cccc(Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.56
HSD11B1 P28845 1/20 0.56
PGR P06401 4/20 0.55
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
LMNA P02545 1/20 0.54
MMP2 P08253 1/20 0.53
NFE2L2 Q16236 6/20 0.51
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
HTR6 P50406 1/20 0.48
ABCC9 O60706 1/20 0.48
ABCC8 Q09428 1/20 0.48
KCNJ11 Q14654 1/20 0.48
KCNJ8 Q15842 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435391 1.00 AKR1B1 (0.56) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL10974178 0.95 HSD11B1 (0.61) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL3834491 0.93 HTR6 (0.61) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL29408747 0.91 ALDH1A1 (0.67) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL2035375 0.91 ALDH1A1 (0.67) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL10945882 0.88 MAPT (0.60) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL693733 0.86 HSD11B1 (0.50) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL3155458 0.86 PGR (0.61) HSD11B1PGRALDH1A1MEN1KMT2A
SCHEMBL8866046 0.86 MEN1 (0.66) AKR1B1HSD11B1PGRALDH1A1MEN1
SCHEMBL3446020 0.86 HSD11B1 (0.57) AKR1B1HSD11B1PGRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1080939-B1 THERMAL RECORDING MATERIAL JUJO PAPER CO LTD (JP) 2007-01-03 EP claimed
EP-1092553-B1 THERMAL RECORDING MATERIAL JUJO PAPER CO LTD (JP) 2006-09-20 EP claimed
EP-1092552-B1 THERMAL RECORDING MATERIAL JUJO PAPER CO LTD (JP) 2004-09-29 EP claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
EP-0079144-B1 PROCESS FOR PRODUCING AROMATIC SULFIDE POLYMERS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-01-29 EP claimed
US-4451640-A Process for producing aromatic sulfide polymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-29 US claimed
JP-60055029-A None JP disclosed
JP-60055030-A None JP disclosed
CN-111918889-B Alkenyl group-containing compound, curable resin composition, and cured product thereof 日本化药株式会社 2022-12-20 CN disclosed
US-20210322933-A1 ZWITTERION-FUNCTIONALIZED COPOLYMER HOLLOW-FIBER MEMBRANES AND ASSOCIATED METHOD CYTIVA SWEDEN AB (SE) 2021-10-21 US disclosed
EP-3794056-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES Cytiva Sweden AB (SE) 2021-03-24 EP disclosed
US-20210079220-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES CYTIVA SWEDEN AB (SE) 2021-03-18 US disclosed
JP-S6055030-A PRODUCTION OF AROMATIC SULFIDE POLYMER KUREHA CHEM IND CO LTD 1985-03-29 JP disclosed
US-4495332-A HIGH MOLECULAR WEIGHT POLYMERS USING A WATER-CONTAINING APROTIC SOLVENT AND A METAL CARBONATE-METAL SALT MIXTURE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-01-22 US disclosed
US-4451640-A Process for producing aromatic sulfide polymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-29 US disclosed
EP-0100536-A2 Process for producing aromatic sulfide polymers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-02-15 EP disclosed
EP-0079144-A1 Process for producing aromatic sulfide polymers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-05-18 EP disclosed
US-4287366-A BY OXIDATION OF THE CORRESPONDING SULFIDE OR SULFOXIDE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF AN ALKALI METAL HYDROXIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1981-09-01 US disclosed