Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 18/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004415 | 0.91 | GPR142 (0.51) | GPR142FAAHCYP2D6 | |
| SCHEMBL16004073 | 0.89 | GPR142 (0.60) | GPR142FAAHCYP2D6 | |
| SCHEMBL16004278 | 0.89 | GPR142 (0.59) | GPR142FAAH | |
| SCHEMBL16004070 | 0.84 | GPR142 (0.49) | GPR142FAAHCYP2D6 | |
| SCHEMBL16004071 | 0.83 | GPR142 (0.60) | GPR142FAAHCYP2D6 | |
| SCHEMBL16004285 | 0.82 | CREBBP (0.54) | — | |
| SCHEMBL16004269 | 0.79 | RIPK1 (0.46) | GPR142 | |
| SCHEMBL16004055 | 0.79 | PIK3CA (0.49) | GPR142 | |
| SCHEMBL16004068 | 0.79 | MAPT (0.49) | GPR142 | |
| SCHEMBL16004284 | 0.78 | GPR142 (0.42) | GPR142FAAHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |