Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 13/20 | 0.59 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004070 | 0.91 | GPR142 (0.49) | GPR142FAAHNAMPTNPC1RAB9A | |
| SCHEMBL16004073 | 0.90 | GPR142 (0.60) | GPR142FAAH | |
| SCHEMBL16004071 | 0.90 | GPR142 (0.60) | GPR142FAAHNAMPTNPC1RAB9A | |
| SCHEMBL16004282 | 0.89 | GPR142 (0.54) | GPR142FAAH | |
| SCHEMBL16004068 | 0.87 | MAPT (0.49) | GPR142NAMPTTSHRNPC1RAB9A | |
| SCHEMBL16004285 | 0.86 | CREBBP (0.54) | — | |
| SCHEMBL16004052 | 0.85 | PIK3CA (0.52) | TSHR | |
| SCHEMBL16004269 | 0.84 | RIPK1 (0.46) | GPR142TSHRPOLBSMN1; SMN2 | |
| SCHEMBL16004284 | 0.84 | GPR142 (0.42) | GPR142FAAH | |
| SCHEMBL16004233 | 0.84 | GPR142 (0.47) | GPR142FAAHTSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133414-A2 | HETEROCYCLIC TGR5 BILE ACID RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR THE PRODUCTION AND USE THEREOF | АЛЛА ХЕМ ЛЛС (US) | 2014-09-04 | — | — | WO | disclosed |