Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | HTR2A | P28223 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14436458 | 0.87 | SLC6A4 (0.38) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19057963 | 0.73 | SLC6A4 (0.41) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL16004751 | 0.72 | HTR2A (0.37) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL13924849 | 0.70 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL19057964 | 0.69 | AR (0.41) | — | |
| SCHEMBL19057972 | 0.67 | AR (0.42) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL27496884 | 0.66 | SLC6A4 (0.44) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5836497 | 0.65 | HTR2A (0.68) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL14437176 | 0.63 | PLA2G7 (0.41) | — | |
| SCHEMBL16004745 | 0.62 | SLC6A4 (0.45) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014134313-A1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC. (US) | 2014-09-04 | — | — | WO | disclosed |