Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534703 | 0.84 | CSNK2A1 (0.40) | CSNK2A1PKMMPOSLC6A4ALDH1A1 | |
| SCHEMBL30814733 | 0.84 | CSNK2A1 (0.40) | CSNK2A1PKMMPOSLC6A4ALDH1A1 | |
| SCHEMBL19926527 | 0.81 | MPO (0.42) | NAAAPKMMPOSLC6A4ALDH1A1 | |
| SCHEMBL29700948 | 0.79 | IDO1 (0.48) | MPOSLC6A4ALDH1A1MAPTIDO1 | |
| SCHEMBL2112768 | 0.79 | CSNK2A1 (0.51) | CSNK2A1ALDH1A1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL548158 | 0.79 | IDO1 (0.48) | MPOSLC6A4ALDH1A1MAPTIDO1 | |
| Hydrochloric Acid SCHEMBL17204528 | 0.78 | IDO1 (0.50) | MPOSLC6A4ALDH1A1MAPTIDO1 | |
| SCHEMBL3076688 | 0.78 | CA3 (0.46) | MPOSLC6A4MAPTIDO1AGXT | |
| SCHEMBL25275619 | 0.76 | CSNK2A1 (0.40) | CSNK2A1ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL1569635 | 0.76 | CYP2A6 (0.49) | CSNK2A1SLC6A4MAPTHTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675288-A | 2-((2-(bi(2-picolyl) amino) ethyl) amino)-4-(3,6,6-trimethyl-4-oxyl-4,5,6,7-tetrahydroindazolyl) benzamide and preparation as well as application | UNIV BEIJING NORMAL | 2012-09-19 | — | — | CN | claimed |
| US-20250120980-A1 | DIBENZODIAZEPINE COMPOUNDS AND USE IN INTERFERON ACTIVATOR PROTEIN AGONISTS THEREOF | HEBEI GRANDIOS PHARMA CO, LTD. (CN) | 2025-04-17 | — | — | US | disclosed |
| CN-117402116-A | Process for the preparation of dibenzoazepine compounds and their use as interferon activator protein agonists | 河北中科金辉药业有限公司 | 2024-01-16 | — | — | CN | disclosed |
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | FMC CORP (US) | 2018-11-01 | — | — | US | disclosed |
| US-10015966-B2 | Fungicidal pyrazole mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-07-10 | — | — | US | disclosed |
| CN-106008299-B | It is used to prepare the intermediate of antifungal pyrazoles | 杜邦公司 | 2018-05-11 | — | — | CN | disclosed |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | DU PONT (US) | 2017-09-14 | — | — | US | disclosed |
| US-20170263871-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE | TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2017-09-14 | — | — | US | disclosed |
| EP-2809157-B1 | FUNGICIDAL PYRAZOLE MIXTURES | DU PONT (US) | 2017-09-06 | — | — | EP | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20120035214-A1 | RENIN INHIBITORS | MERCK CANADA INC. (CA) | 2012-02-09 | — | — | US | disclosed |
| EP-2413941-A1 | RENIN INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-8063035-B2 | Triazolyl aminopyrimidine compounds | ELI LILLY AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| WO-2010114978-A1 | RENIN INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |
| US-20100087431-A1 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY | 2010-04-08 | — | — | US | disclosed |
| CN-101679395-A | triazolyl aminopyrimidine compounds | LILLY CO ELI | 2010-03-24 | — | — | CN | disclosed |
| EP-2155734-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008144223-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-11-27 | — | — | WO | disclosed |
| US-4238611-A | Polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepine | SPOFA, UNITED PHARMACEUTICAL WORKS (CS) | 1980-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250120980-A1 | DIBENZODIAZEPINE COMPOUNDS AND USE IN INTERFERON ACTIVATOR PROTEIN AGONISTS THEREOF | STING1, IRF3, IFNAR1 | CSNK2A1 503/4885NAAA 2027/4885PKM 3369/4885 |
| US-20170263871-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE | OR10J3, RPS10, OR51E2 | CSNK2A1 1073/4885NAAA 3610/4885PKM 3697/4885 |
| US-20120035214-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | CSNK2A1 4458/4885NAAA 1138/4885PKM 2635/4885 |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | NOD1, AFF1, MAST1 | CSNK2A1 3900/4885NAAA 1008/4885PKM 3343/4885 |
| US-10015966-B2 | Fungicidal pyrazole mixtures | CYP1B1, CBR3, CBR1 | CSNK2A1 3111/4885NAAA 1462/4885PKM 2523/4885 |
| US-20100087431-A1 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | DPYD, TP53, TYMP | CSNK2A1 2645/4885NAAA 3291/4885PKM 1694/4885 |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | CYP1B1, CBR3, CBR1 | CSNK2A1 3111/4885NAAA 1462/4885PKM 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.