SCHEMBL16009653

SCHEMBL16009653

COc1cc(C)c(Cl)c(OC)c1.[MgH2]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
LMNA P02545 3/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
GLA P06280 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
NQO2 P16083 2/20 0.41
CYP19A1 P11511 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133298 0.98 ALDH1A1 (0.45) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL3749321 0.84 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDCA12CA1
SCHEMBL15883267 0.84 ALDH1A1 (0.53) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL16072317 0.80 ELANE (0.42) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL16134065 0.78 ALDH1A1 (0.42) ALDH1A1KDM4EGAAHPGDKMT2A
SCHEMBL1911832 0.78 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL14500122 0.77 ACHE (0.52) ALDH1A1GAAHPGDKMT2AMAPT
SCHEMBL16958899 0.77 ALDH1A1 (0.46) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL18523730 0.76 ALDH1A1 (0.43) ALDH1A1LMNAKDM4EGAAHPGD
SCHEMBL15120000 0.75 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE Unilever PLC, a company registered in England and Wales under company no. 41424 of (GB) 2016-01-13 EP disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 ALDH1A1 415/4885LMNA 338/4885KDM4E 2983/4885
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 ALDH1A1 415/4885LMNA 338/4885KDM4E 2983/4885
US-10470986-B2 Resorcinol compounds for dermatological use NQO1, RBP4, KEAP1 ALDH1A1 415/4885LMNA 338/4885KDM4E 2983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.