SCHEMBL16009749

SCHEMBL16009749

CCc1c(OC)cc(OC)cc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.39
▸ HTR2C P28335 1/20 0.39
▸ AR P10275 2/20 0.36
▸ CA1 P00915 2/20 0.36
▸ CA2 P00918 2/20 0.36
▸ CA12 O43570 1/20 0.35
▸ CA7 P43166 1/20 0.35
▸ CA9 Q16790 1/20 0.35
▸ CA14 Q9ULX7 1/20 0.35
▸ CRHR1 P34998 2/20 0.35
▸ EPHX2 P34913 1/20 0.35
▸ AKR1B10 O60218 1/20 0.35
▸ AKR1C4 P17516 1/20 0.35
▸ AKR1C3 P42330 1/20 0.35
▸ AKR1C2 P52895 1/20 0.35
▸ AKR1C1 Q04828 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15180046 0.84 CA1 (0.50) HTR2ACA1CA2CA12CA7
SCHEMBL25745801 0.82 ACHE (0.41) HTR2AHTR2CARCRHR1ALDH1A1
SCHEMBL22017132 0.82 HTR2A (0.39) HTR2AHTR2CCRHR1
SCHEMBL19871663 0.81 HTR2A (0.38) HTR2AHTR2CARMEN1KMT2A
SCHEMBL5185794 0.80 ALDH1A1 (0.48) CA1CA2CA12CA7CA9
SCHEMBL16011478 0.80 ERN1 (0.38) HTR2AHTR2CEPHX2ALDH1A1
SCHEMBL25745865 0.79 HTR2A (0.37) HTR2AHTR2CCRHR1
SCHEMBL1041890 0.74 ENPP3 (0.39) HTR2AHTR2CARCA1CA2
SCHEMBL1042619 0.74 CA1 (0.38) HTR2AHTR2CARCA1CA2
SCHEMBL13067435 0.73 ALDH1A1 (0.40) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 — — US disclosed
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 — — US disclosed
CN-105142603-B Resorcinol compounds for dermatological use 荷兰联合利华有限公司 2018-10-19 — — CN disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 — — EP disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 — — EP disclosed
EP-2964182-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE Unilever PLC, a company registered in England and Wales under company no. 41424 of (GB) 2016-01-13 — — EP disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 — — US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 — — US disclosed
CN-105142603-A Resorcinol compounds for dermatological use UNILEVER NV 2015-12-09 — — CN disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 — — WO disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 — — WO disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 — — US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 HTR2A 4010/4885HTR2C 4586/4885AR 2469/4885
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 HTR2A 4010/4885HTR2C 4586/4885AR 2469/4885
US-10470986-B2 Resorcinol compounds for dermatological use NQO1, RBP4, KEAP1 HTR2A 4010/4885HTR2C 4586/4885AR 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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