SCHEMBL16010609

SCHEMBL16010609

Cc1cc(O)cc(O)c1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
KDM4E B2RXH2 2/20 0.51
MAPT P10636 2/20 0.51
ALDH1A1 P00352 1/20 0.51
ALOX5 P09917 1/20 0.50
BCL2 P10415 1/20 0.47
BCL2L1 Q07817 1/20 0.47
IDH1 O75874 3/20 0.44
NQO1 P15559 1/20 0.43
GAA P10253 2/20 0.42
GLA P06280 1/20 0.42
HSD17B3 P37058 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ERAP1 Q9NZ08 1/20 0.42
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
SLC5A1 P13866 1/20 0.41
SLC5A2 P31639 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589520 0.90 THRA (0.49) LMNAKDM4EMAPTALDH1A1ALOX5
SCHEMBL278266 0.86 ALOX5 (0.59) KDM4EMAPTALDH1A1ALOX5BCL2
SCHEMBL31154580 0.85 BCL2 (0.47) KDM4EMAPTALDH1A1ALOX5BCL2
SCHEMBL10628131 0.81 KDM4E (0.48) LMNAKDM4EMAPTALDH1A1ALOX5
SCHEMBL12824842 0.80 MEN1 (0.51) LMNAALOX5BCL2BCL2L1IDH1
SCHEMBL11119196 0.80 KDM4E (0.47) LMNAKDM4EMAPTALDH1A1ALOX5
SCHEMBL27927792 0.78 BCL2 (0.47) KDM4EMAPTALDH1A1ALOX5BCL2
SCHEMBL10477351 0.77 KDM4E (0.45) LMNAKDM4EMAPTALDH1A1ALOX5
SCHEMBL1550879 0.77 ALOX5 (0.46) KDM4EMAPTALDH1A1ALOX5BCL2
SCHEMBL31083555 0.77 BCL2 (0.50) ALOX5BCL2BCL2L1IDH1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE Unilever PLC, a company registered in England and Wales under company no. 41424 of (GB) 2016-01-13 EP disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 LMNA 338/4885KDM4E 2983/4885MAPT 354/4885
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 LMNA 338/4885KDM4E 2983/4885MAPT 354/4885
US-10470986-B2 Resorcinol compounds for dermatological use NQO1, RBP4, KEAP1 LMNA 338/4885KDM4E 2983/4885MAPT 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.