SCHEMBL278266

SCHEMBL278266

Oc1cc(O)c(Cc2ccccc2)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
BCL2 P10415 1/20 0.56
BCL2L1 Q07817 1/20 0.56
IDH1 O75874 2/20 0.52
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CALM1 P0DP23 1/20 0.48
GAA P10253 1/20 0.47
SLC5A1 P13866 1/20 0.47
SLC5A2 P31639 1/20 0.47
ALOX15 P16050 2/20 0.46
MEN1 O00255 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HNF4A P41235 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8427398 0.88 SLC28A3 (0.54) ALOX5BCL2BCL2L1IDH1MAPT
SCHEMBL10775222 0.86 ALOX5 (0.44) ALOX5BCL2BCL2L1IDH1MAPT
SCHEMBL31544990 0.86 IDH1 (0.63) ALOX5BCL2BCL2L1IDH1CALM1
SCHEMBL16010609 0.86 LMNA (0.53) ALOX5BCL2BCL2L1IDH1MAPT
SCHEMBL18044787 0.84 SLC28A3 (0.61) ALOX5MAPTKDM4EALDH1A1GAA
SCHEMBL22139363 0.82 BCL2 (0.56) ALOX5BCL2BCL2L1IDH1KDM4E
SCHEMBL16010051 0.82 ALOX5 (0.46) ALOX5BCL2BCL2L1IDH1MAPT
SCHEMBL875676 0.81 BCL2 (0.54) ALOX5BCL2BCL2L1IDH1MAPT
SCHEMBL9742762 0.80 SLC28A3 (0.57) ALOX5BCL2BCL2L1MAPTGAA
SCHEMBL8427400 0.79 HSPA5 (0.48) ALOX5BCL2BCL2L1HIF1ASLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094254-B Carbonoside compounds, and preparation and application thereof 中国医学科学院药物研究所 2023-05-05 CN disclosed
CN-111286495-B Aloe C-glycosyltransferase sequence and application thereof in catalyzing C-glycosylation 中国医学科学院药物研究所 2022-05-20 CN disclosed
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
CN-112094254-A Carbon glycoside compounds and preparation and application thereof 中国医学科学院药物研究所 2020-12-18 CN disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
US-20200199058-A1 SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES NITTO DENKO CORPORATION (JP) 2020-06-25 US disclosed
CN-111286495-A Aloe C-glycosyltransferase sequence and application thereof in catalyzing C-glycosylation 中国医学科学院药物研究所 2020-06-16 CN disclosed
US-7368205-B2 Polyamide resin, positive-working photosensitive resin composition, method for producing pattern-formed resin film, semiconductor device, display device, and method for producing the semiconductor device and the display device SUMITOMO BAKELITE CO., LTD. (JP) 2008-05-06 US disclosed
US-7368205-B2 Polyamide resin, positive-working photosensitive resin composition, method for producing pattern-formed resin film, semiconductor device, display device, and method for producing the semiconductor device and the display device SUMITOMO BAKELITE CO., LTD. (JP) 2008-05-06 US disclosed
US-7361445-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY (JP) 2008-04-22 US disclosed
US-7361445-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY (JP) 2008-04-22 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080076849-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-7238455-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY, LTD. (JP) 2007-07-03 US disclosed
US-7238455-B2 Mixture of alkali soluble resin, quinonediazide compound and alcohol SUMITOMO BAKELITE COMPANY, LTD. (JP) 2007-07-03 US disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C ALOX5 1994/4885BCL2 715/4885BCL2L1 1507/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR ALOX5 2752/4885BCL2 682/4885BCL2L1 1183/4885
US-20200199058-A1 SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES SQLE, FDFT1, ALDH1A2 ALOX5 1459/4885BCL2 4709/4885BCL2L1 3651/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 ALOX5 3694/4885BCL2 330/4885BCL2L1 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.