SCHEMBL16013197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17411125	0.93	CYP1A2 (0.44)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL17404814	0.88	CYP1A2 (0.31)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL27445171	0.84	ALOX5 (0.40)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL20502641	0.80	CNR1 (0.38)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL21916203	0.78	CNR1 (0.35)	ALOX5PTGS1PTGS2CNR1CNR2
	SCHEMBL15466818	0.78	ALOX5 (0.35)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL24916787	0.77	CYP1A2 (0.38)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL25976495	0.76	CNR1 (0.34)	CYP2D6CYP1A2CYP2C19MAPTCYP2C9
	SCHEMBL14438152	0.76	GPR84 (0.42)	MAPTKDM4EPAMTSHRMEN1
	SCHEMBL8665617	0.76	DGKA (0.58)	MAPTHSD17B10ALDH1A1KDM4EPAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.