Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024360 | 0.83 | PDE3B (0.33) | FABP4FABP3 | |
| SCHEMBL16013937 | 0.78 | PNMT (0.35) | CA1CA2CA9 | |
| SCHEMBL16013533 | 0.77 | RIPK1 (0.37) | FABP4FABP3 | |
| SCHEMBL3058364 | 0.77 | CRBN (0.37) | CA1CA2CA7CA9GSK3B | |
| SCHEMBL16013293 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL16013962 | 0.74 | TDP2 (0.34) | — | |
| SCHEMBL16013778 | 0.70 | — | — | |
| SCHEMBL16013858 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL16013802 | 0.70 | — | — | |
| SCHEMBL16196832 | 0.70 | ACHE (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| EP-2964025-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014135095-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | DDT, DHODH, ACHE | FABP4 2641/4885FABP3 1964/4885POLB 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.