Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859335 | 0.95 | POLB (0.55) | POLBKMT2AFFAR1LDHAALDH1A1 | |
| SCHEMBL11432241 | 0.85 | FFAR1 (0.65) | FFAR1PPARAPPARDACACBPPARG | |
| SCHEMBL14640275 | 0.84 | FFAR1 (0.53) | KMT2AFFAR1PPARAPPARDLDHA | |
| SCHEMBL159833 | 0.80 | PTGS2 (0.55) | POLBKMT2AMAPTLMNAELANE | |
| SCHEMBL11237591 | 0.79 | TBXAS1 (0.59) | FFAR1LDHALMNATBXAS1 | |
| SCHEMBL671002 | 0.79 | SLC7A5 (0.61) | POLBKMT2ALDHAALDH1A1HSP90AA1 | |
| SCHEMBL22645606 | 0.79 | SLC7A5 (0.61) | POLBKMT2ALDHAALDH1A1HSP90AA1 | |
| SCHEMBL450849 | 0.79 | SLC7A5 (0.61) | POLBKMT2ALDHAALDH1A1HSP90AA1 | |
| SCHEMBL4372393 | 0.78 | LMNA (0.52) | POLBKMT2ALDHAALDH1A1HSP90AA1 | |
| SCHEMBL663059 | 0.78 | LDHA (0.73) | FFAR1PPARALDHAACACBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256912-A1 | Stabilized Variant MAML Peptides and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256912-A1 | Stabilized Variant MAML Peptides and Uses Thereof | NOTCH1, MDN1, NOTCH2 | POLB 4521/4885KMT2A 3650/4885FFAR1 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.