Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166122 | 0.82 | TDP1 (0.57) | USP2TDP1LMNAKMT2AGAA | |
| SCHEMBL29381145 | 0.82 | TDP1 (0.57) | USP2TDP1LMNAKMT2AGAA | |
| SCHEMBL20208276 | 0.81 | TDP1 (0.49) | TNFTDP1LMNAKDM4EKMT2A | |
| SCHEMBL2779921 | 0.79 | NPC1 (0.53) | USP2KDM4EGAAALDH1A1 | |
| SCHEMBL10299247 | 0.78 | KDM4E (0.57) | TDP1LMNAKDM4EKMT2AGAA | |
| SCHEMBL12552816 | 0.76 | CASP3 (0.56) | LMNAKMT2AMEN1ALDH1A1CASP3 | |
| SCHEMBL12540869 | 0.75 | POLB (0.53) | TDP1KDM4EKMT2AGAAHTT | |
| SCHEMBL439776 | 0.74 | ANPEP (0.34) | USP2TDP1LMNACASP1CASP7 | |
| SCHEMBL17300647 | 0.74 | BCL2 (0.41) | USP2TDP1LMNAKDM4EKMT2A | |
| Sulfuric Acid SCHEMBL29217860 | 0.73 | LMNA (0.51) | TDP1LMNAKMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795247-B2 | Polyolefin dispersants and methods of making and using thereof | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2023-10-24 | — | — | US | disclosed |
| US-11795247-B2 | Polyolefin dispersants and methods of making and using thereof | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2023-10-24 | — | — | US | disclosed |
| US-20210189030-A1 | Polyolefin Dispersants and Methods of Making and Using Thereof | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2021-06-24 | — | — | US | disclosed |
| US-10875946-B2 | Polyolefin dispersants and methods of making and using thereof | CHEVRON ORONITE COMPANY LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20190284314-A1 | Polyolefin Dispersants and Methods of Making and Using Thereof | CHEVRON ORONITE COMPANY LLC. | 2019-09-19 | — | — | US | disclosed |
| US-20180148408-A1 | DIRECT INHIBITORS OF KEAP1-NRF2 INTERACTION AS ANTIOXIDANT INFLAMMATION MODULATORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2018-05-31 | — | — | US | disclosed |
| US-20180148408-A1 | DIRECT INHIBITORS OF KEAP1-NRF2 INTERACTION AS ANTIOXIDANT INFLAMMATION MODULATORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2018-05-31 | — | — | US | disclosed |
| US-20140256767-A1 | DIRECT INHIBITORS OF KEAP1-NRF2 INTERACTION AS ANTIOXIDANT INFLAMMATION MODULATORS | THE BROAD INSTITUTE, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148408-A1 | DIRECT INHIBITORS OF KEAP1-NRF2 INTERACTION AS ANTIOXIDANT INFLAMMATION MODULATORS | KEAP1, NFE2L2, HMOX1 | USP2 1709/4885TNF 701/4885TDP1 3896/4885 |
| US-20140256767-A1 | DIRECT INHIBITORS OF KEAP1-NRF2 INTERACTION AS ANTIOXIDANT INFLAMMATION MODULATORS | KEAP1, NFE2L2, HMOX1 | USP2 1709/4885TNF 701/4885TDP1 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.