Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.45 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445316 | 0.85 | MAPK1 (0.58) | MAPK1TSHRKIF18AVCAM1L3MBTL1 | |
| SCHEMBL6557915 | 0.84 | MAPK1 (0.49) | MAPK1TSHRKIF18AVCAM1L3MBTL1 | |
| SCHEMBL2653845 | 0.81 | CCR2 (0.55) | MAPK1TSHRKIF18AVCAM1L3MBTL1 | |
| SCHEMBL13945797 | 0.79 | ALDH1A1 (0.50) | MAPK1TSHRL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12737451 | 0.79 | TSHR (0.62) | TSHRL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL446475 | 0.79 | TDP1 (0.55) | MAPK1TSHRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL15356395 | 0.78 | TDP1 (0.53) | MAPK1TSHRL3MBTL1ALDH1A1PDE7A | |
| SCHEMBL16955053 | 0.78 | MEN1 (0.42) | MAPK1TSHRL3MBTL1ALDH1A1LMNA | |
| SCHEMBL395910 | 0.78 | ALDH1A1 (0.59) | MAPK1TSHRL3MBTL1ALDH1A1PDE7A | |
| SCHEMBL9905069 | 0.78 | HTT (0.50) | MAPK1TSHRL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| US-9693556-B2 | Herbicidal pyridazinone derivatives | SYNGENTA LIMITED (GB) | 2017-07-04 | — | — | US | disclosed |
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256546-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | PRDX6, PRDX1, CBR3 | MAPK1 1853/4885TSHR 391/4885KIF18A 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.