Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.40 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16019793 | 0.90 | DGAT1 (0.49) | DGAT1ALDH1A1STIM1ORAI1USP36 | |
| SCHEMBL14881443 | 0.89 | STIM1 (0.46) | DGAT1ALDH1A1DDR1STIM1ORAI1 | |
| SCHEMBL14887335 | 0.88 | BACE1 (0.42) | ALDH1A1STIM1ORAI1ORAI2SMO | |
| SCHEMBL16017234 | 0.83 | HSD17B10 (0.50) | ALDH1A1STIM1ORAI1ORAI2IL2 | |
| SCHEMBL16020570 | 0.81 | STIM1 (0.59) | DGAT1ALDH1A1DDR1STIM1ORAI1 | |
| SCHEMBL14887769 | 0.81 | STIM1 (0.43) | STIM1ORAI1ORAI2AHRIL2 | |
| SCHEMBL16019778 | 0.81 | GRM1 (0.49) | STIM1ORAI1ORAI2 | |
| SCHEMBL16020572 | 0.79 | STIM1 (0.48) | DGAT1ALDH1A1DDR1STIM1ORAI1 | |
| SCHEMBL16019775 | 0.79 | GAA (0.46) | ALDH1A1STIM1ORAI1ORAI2AHR | |
| SCHEMBL16019776 | 0.79 | ALDH1A1 (0.56) | ALDH1A1STIM1ORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | DGAT1 1057/4885ALDH1A1 4409/4885DDR1 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.