Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 9/20 | 0.49 |
| ▸ | MMP2 | P08253 | 9/20 | 0.49 |
| ▸ | MMP9 | P14780 | 9/20 | 0.49 |
| ▸ | EGFR | P00533 | 8/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029571 | 1.00 | RAB9A (0.58) | RAB9AKMT2AALDH1A1LMNAHTT | |
| SCHEMBL5094443 | 0.77 | MAPT (0.50) | RAB9AKMT2AALDH1A1LMNAHTT | |
| SCHEMBL28449565 | 0.70 | MMP1 (0.71) | RAB9AKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL28449561 | 0.70 | MMP1 (0.71) | RAB9AKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL11576171 | 0.68 | MMP1 (0.71) | RAB9AKMT2AMMP1MMP2MMP9 | |
| SCHEMBL11575343 | 0.68 | MMP1 (0.71) | RAB9AKMT2AMMP1MMP2MMP9 | |
| SCHEMBL13755322 | 0.68 | MMP1 (0.63) | RAB9AKMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL29564507 | 0.68 | MAPT (0.60) | RAB9AKMT2AALDH1A1LMNAHTT | |
| SCHEMBL10492424 | 0.67 | MMP1 (0.80) | RAB9AMMP1MMP2MMP9EGFR | |
| N-Phenylcinnamamide SCHEMBL4205896 | 0.67 | MMP1 (1.00) | RAB9AKMT2ASMN1; SMN2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970316-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20160145257-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. | 2016-05-26 | — | — | US | disclosed |
| US-20140275528-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145257-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | TRPC5, TRPC7, TRPC4 | RAB9A 3823/4885KMT2A 4201/4885ALDH1A1 1647/4885 |
| US-20140275528-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | TRPC5, TRPC7, TRPC4 | RAB9A 3823/4885KMT2A 4201/4885ALDH1A1 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.