Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15914634 | 0.81 | TDP1 (0.32) | TDP1 | |
| SCHEMBL711280 | 0.79 | CA4 (0.35) | TDP1 | |
| SCHEMBL706901 | 0.77 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL19927143 | 0.76 | — | — | |
| SCHEMBL19927058 | 0.76 | — | — | |
| SCHEMBL704955 | 0.76 | CA4 (0.37) | — | |
| SCHEMBL19926989 | 0.74 | — | — | |
| SCHEMBL705570 | 0.74 | MAPK1 (0.32) | — | |
| SCHEMBL705403 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL28728736 | 0.72 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387855-B1 | FOR KERATIN FIBERS | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | claimed |
| JP-4229640-A | — | — | None | — | — | JP | disclosed |
| US-7918903-B2 | Composition for the oxidation dyeing of keratin fibers comprising at least one fatty substance and at least one N,N bis(beta-hydroxyethyl)-para-phenylenediamine | L'OREAL, S.A. (FR) | 2011-04-05 | — | — | US | disclosed |
| US-20100154142-A1 | Composition for the oxidation dyeing of keratin fibers comprising at least one fatty substance and at least one N,N-bis(beta-hydroxyethyl)-para-phenylenediamine | L'OREAL S.A. (FR) | 2010-06-24 | — | — | US | disclosed |
| EP-0940423-B1 | Emulsions of silicones with non-aqueous hydroxylic solvents | GEN ELECTRIC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-6271295-B1 | SILICONE ELASTOMERS AND NONAQUEOUS ORGANIC HYDROLYTIC SOLVENT | GENERAL ELECTRIC COMPANY | 2001-08-07 | — | — | US | disclosed |
| EP-0940423-A2 | Emulsions of silicones with non-aqueous hydroxylic solvents | GENERAL ELECTRIC COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| JP-H04229640-A | ELECTRONIC DEVICE PRODUCT | AMERICAN TELEPH & TELEGR CO <ATT> | 1992-08-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100154142-A1 | Composition for the oxidation dyeing of keratin fibers comprising at least one fatty substance and at least one N,N-bis(beta-hydroxyethyl)-para-phenylenediamine | KRT18, PLOD3, CKMT1A; CKMT1B | TDP1 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.