SCHEMBL1603240

SCHEMBL1603240

O=C(CCCI)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PSMB8 P28062 2/20 0.33
PSMB5 P28074 1/20 0.32
ALOX12 P18054 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13574291 0.95 SMN1; SMN2 (0.35) KMT2ASMN1; SMN2PSMB8PSMB5
SCHEMBL1603588 0.93 SMN1; SMN2 (0.38) KMT2ASMN1; SMN2PSMB8PSMB5
SCHEMBL2608502 0.89 LMNA (0.34) PSMB8PSMB5MGLL
SCHEMBL22777675 0.88 SMN1; SMN2 (0.36) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12
SCHEMBL34383 0.88 SMN1; SMN2 (0.36) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12
SCHEMBL290461 0.88 SMN1; SMN2 (0.40) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12
SCHEMBL905722 0.86 SMN1; SMN2 (0.42) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12
SCHEMBL379163 0.86 SMN1; SMN2 (0.42) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12
SCHEMBL4960230 0.86 SMN1; SMN2 (0.42) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12
SCHEMBL1870550 0.86 SMN1; SMN2 (0.42) KMT2ASMN1; SMN2PSMB8PSMB5ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309171-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2019-10-10 US disclosed
US-20120231459-A1 CHEMILUMINESCENT PROBES FOR MULTIPLEX MOLECULAR QUANTIFICATION AND USES THEREOF GEN-PROBE INCORPORATED (US) 2012-09-13 US disclosed
US-20110082279-A1 Chemiluminescent Compounds GEN-PROBE INCORPORATED (US) 2011-04-07 US disclosed
EP-1658503-B1 CHEMILUMINESCENT COMPOUNDS MOLECULAR LIGHT TECH RES LTD (GB) 2009-11-18 EP disclosed
US-20070166759-A1 Chemiluminescent compounds GEN-PROBE CARDIFF, LTD. (GB) 2007-07-19 US disclosed
EP-1658503-A1 CHEMILUMINESCENT COMPOUNDS Molecular Light Technology Research Limited (GB) 2006-05-24 EP disclosed
WO-2005022161-A1 CHEMILUMINESCENT COMPOUNDS MOLECULAR LIGHT TECHNOLOGY RESEARCH LIMITED (GB) 2005-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070166759-A1 Chemiluminescent compounds CBR3, CBR1, LTC4S KMT2A 3854/4885SMN1; SMN2 4725/4885PSMB8 4466/4885
US-20120231459-A1 CHEMILUMINESCENT PROBES FOR MULTIPLEX MOLECULAR QUANTIFICATION AND USES THEREOF HMBS, NOD1, DCLRE1B KMT2A 3735/4885SMN1; SMN2 4855/4885PSMB8 4014/4885
US-20110082279-A1 Chemiluminescent Compounds CBR3, LTC4S, CBR1 KMT2A 3896/4885SMN1; SMN2 4695/4885PSMB8 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.