SCHEMBL1603369

SCHEMBL1603369

CO[Si](CCCNCCN)(OC)OCCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.44
DRD2 P14416 2/20 0.42
DRD4 P21917 2/20 0.42
DRD3 P35462 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL28046221 0.97 SIGMAR1 (0.41) SIGMAR1DRD2DRD4DRD3MEN1
Heptane SCHEMBL28860810 0.93 SIGMAR1 (0.48) SIGMAR1DRD2DRD4DRD3
SCHEMBL447454 0.89 DRD2 (0.46) SIGMAR1DRD2DRD4DRD3MEN1
SCHEMBL28175344 0.88 SIGMAR1 (0.44) SIGMAR1DRD2DRD4DRD3
SCHEMBL37761 0.88 SIGMAR1 (0.42) SIGMAR1DRD2DRD4DRD3
SCHEMBL614447 0.87 MAOA (0.46)
SCHEMBL28789259 0.85 SIGMAR1 (0.39) SIGMAR1DRD2DRD4DRD3MEN1
SCHEMBL5203912 0.83 MAOA (0.45) SIGMAR1DRD4MEN1KMT2A
SCHEMBL31028360 0.83 MEN1 (0.42) SIGMAR1MEN1KMT2A
Aniline SCHEMBL28077933 0.82 SIGMAR1 (0.38) SIGMAR1DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110082254-A1 METHOD FOR THE PRODUCTION OF A HIGHLY ABRASION-RESISTANT VEHICLE PAINT, VEHICLE PAINT, AND THE USE THEREOF NANO-X GMBH (DE) 2011-04-07 US disclosed