Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DTYMK | P23919 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16038157 | 1.00 | FBP1 (0.41) | FBP1EIF4ETSHRTP53MAPT | |
| SCHEMBL16038153 | 0.77 | TSHR (0.48) | FBP1EIF4ETSHRMAPTALDH1A1 | |
| SCHEMBL14919172 | 0.76 | MEN1 (0.46) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16037020 | 0.75 | ALDH1A1 (0.37) | TP53ALDH1A1 | |
| SCHEMBL30388619 | 0.74 | FBP1 (0.46) | FBP1TSHRMAPTALDH1A1DTYMK | |
| SCHEMBL593074 | 0.73 | TSHR (0.60) | FBP1TSHRTP53MAPTALDH1A1 | |
| SCHEMBL14918728 | 0.73 | HNF4A (0.53) | TSHRMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14918727 | 0.73 | HNF4A (0.49) | MAPTALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL29073837 | 0.73 | ALDH1A1 (0.41) | TSHRMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL29029506 | 0.73 | FBP1 (0.45) | FBP1TSHRMAPTALDH1A1DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275049-A1 | SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS | ELI LILLY AND COMPANY | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275049-A1 | SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS | RARB, RARA, RARG | FBP1 3271/4885EIF4E 3953/4885TSHR 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.