Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062065 | 0.81 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL31174723 | 0.81 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL14918727 | 0.80 | HNF4A (0.49) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1535274 | 0.77 | RAB9A (0.46) | TSHRMAPTLMNAALDH1A1HPGD | |
| SCHEMBL9746118 | 0.77 | ALDH1A1 (0.56) | TSHRMAPTLMNAHTTDDX3X | |
| SCHEMBL9746112 | 0.77 | ALDH1A1 (0.56) | TSHRMAPTLMNAHTTDDX3X | |
| SCHEMBL16038154 | 0.77 | FBP1 (0.41) | TSHRMAPTEIF4EALDH1A1MEN1 | |
| SCHEMBL16038157 | 0.77 | FBP1 (0.41) | TSHRMAPTEIF4EALDH1A1MEN1 | |
| SCHEMBL14919171 | 0.77 | MEN1 (0.51) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16037019 | 0.76 | ALDH1A1 (0.43) | MAPTLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275049-A1 | SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS | ELI LILLY AND COMPANY | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275049-A1 | SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS | RARB, RARA, RARG | TSHR 283/4885MAPT 4647/4885LMNA 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.