Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16039655 | 0.86 | FLT3 (0.55) | ALDH1A1KDM4EHPGDNPC1MAPT | |
| SCHEMBL16041896 | 0.86 | FLT3 (0.55) | ALDH1A1KDM4EHPGDNPC1MAPT | |
| SCHEMBL1119554 | 0.74 | PTGS2 (0.66) | PTGS1P2RX7NOTUML3MBTL1MAOA | |
| SCHEMBL28331494 | 0.73 | CYP19A1 (0.62) | ALDH1A1NPC1MEN1KMT2AHSD17B10 | |
| Bromide SCHEMBL6256547 | 0.73 | PTGS2 (0.64) | PTGS1P2RX7NOTUML3MBTL1MAOA | |
| SCHEMBL16038524 | 0.72 | KEAP1 (0.48) | PTGS1P2RX7NOTUML3MBTL1MAOA | |
| SCHEMBL16039980 | 0.72 | HSD17B10 (0.42) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL16040535 | 0.70 | BCHE (0.51) | ALDH1A1KDM4EHPGDNPC1PTGS1 | |
| SCHEMBL714849 | 0.70 | P2RX7 (0.45) | PTGS1P2RX7NOTUML3MBTL1MAOA | |
| SCHEMBL16039276 | 0.70 | PTGS1 (0.51) | ALDH1A1KDM4EHPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2019-09-03 | — | — | US | claimed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | claimed |
| US-9763449-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2017-09-19 | — | — | US | claimed |
| US-20160302415-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-10-20 | — | — | US | claimed |
| US-9402397-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-08-02 | — | — | US | claimed |
| US-20160007605-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-01-14 | — | — | US | claimed |
| US-9173401-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2015-11-03 | — | — | US | claimed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | claimed |
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2019-09-03 | — | — | US | disclosed |
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2019-09-03 | — | — | US | disclosed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-9763449-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-9173401-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2015-11-03 | — | — | US | disclosed |
| US-9173401-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2015-11-03 | — | — | US | disclosed |
| WO-2014152115-A1 | N-,C-DISUBSTITUTED AZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007605-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | ALDH1A1 2730/4885KDM4E 1491/4885HPGD 3139/4885 |
| US-20170332639-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | ALDH1A1 2730/4885KDM4E 1491/4885HPGD 3139/4885 |
| US-20140274689-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | ALDH1A1 2730/4885KDM4E 1491/4885HPGD 3139/4885 |
| US-10398144-B2 | N-,C-disubstituted azoles and compositions and methods for controlling nematode pests | CYCS, DNPH1, DDT | ALDH1A1 2730/4885KDM4E 1491/4885HPGD 3139/4885 |
| US-20160302415-A1 | N-,C-DISUBSTITUTED AZOLES AND COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | CYCS, DNPH1, DDT | ALDH1A1 2730/4885KDM4E 1491/4885HPGD 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.