Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873091 | 0.77 | KDM4E (0.43) | PAX8KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL14037359 | 0.73 | KDM4E (0.36) | PAX8KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3565701 | 0.71 | HTR2A (0.39) | PAX8KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1994314 | 0.70 | MEP1B (0.41) | PAX8KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL23611636 | 0.70 | HTR1A (0.33) | — | |
| SCHEMBL16044712 | 0.70 | EGFR (0.32) | PAX8KDM4EPOLB | |
| SCHEMBL31058582 | 0.70 | HTR2A (0.39) | PAX8ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL24102364 | 0.70 | HTR2A (0.39) | PAX8ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL14288597 | 0.68 | KDM4E (0.32) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL475141 | 0.67 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292502-A | Novel 4-aminopyridine and 6-aminopyrimidine carboxylates as herbicides | 美国陶氏益农公司 | 2021-08-24 | — | — | CN | disclosed |
| US-10765114-B2 | 4-amino-6-(pyridyl and 2-substitutedphenyl)-picolinates and 6-amino-2-(pyridyl and 2-substitutedphenyl)-pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2020-09-08 | — | — | US | disclosed |
| US-10765114-B2 | 4-amino-6-(pyridyl and 2-substitutedphenyl)-picolinates and 6-amino-2-(pyridyl and 2-substitutedphenyl)-pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2020-09-08 | — | — | US | disclosed |
| EP-2967057-B1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2018-11-21 | — | — | EP | disclosed |
| EP-2967057-A1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | Dow AgroSciences LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014150809-A1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014150809-A1 | NOVEL 4-AMINOPYRIDINE AND 6-AMINOPYRIMIDINE CARBOXYLATES AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140274703-A1 | NOVEL 4-AMINO-6-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PICOLINATES AND 6-AMINO-2-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274703-A1 | NOVEL 4-AMINO-6-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PICOLINATES AND 6-AMINO-2-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274703-A1 | NOVEL 4-AMINO-6-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PICOLINATES AND 6-AMINO-2-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10765114-B2 | 4-amino-6-(pyridyl and 2-substitutedphenyl)-picolinates and 6-amino-2-(pyridyl and 2-substitutedphenyl)-pyrimidine-4-carboxylates and their use as herbicides | DDT, P2RX6, PLPBP | PAX8 111/4885KDM4E 1211/4885ALDH1A1 951/4885 |
| US-20140274703-A1 | NOVEL 4-AMINO-6-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PICOLINATES AND 6-AMINO-2-(PYRIDYL AND 2-SUBSTITUTEDPHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, PLPBP, P2RX6 | PAX8 119/4885KDM4E 1268/4885ALDH1A1 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.