Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17085404 | 0.78 | RET (0.46) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL14862184 | 0.76 | IDO1 (0.61) | MAPTAPPRETKDR | |
| SCHEMBL14690823 | 0.75 | CYP19A1 (0.42) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL7242379 | 0.74 | ALDH1A1 (0.57) | TP53MAPTTDP1ALDH1A1LMNA | |
| SCHEMBL21738208 | 0.70 | CYP3A4 (0.56) | TP53MAPTTDP1ALDH1A1LMNA | |
| SCHEMBL10608985 | 0.69 | ALDH1A1 (0.67) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL21722487 | 0.69 | CYP2C9 (0.61) | TP53MAPTTDP1ALDH1A1LMNA | |
| SCHEMBL21738284 | 0.68 | CYP3A4 (0.66) | TP53MAPTTDP1ALDH1A1LMNA | |
| SCHEMBL14427922 | 0.67 | ALDH1A1 (0.45) | PDE4APDE4BPDE4CPDE4DTDP1 | |
| SCHEMBL28320416 | 0.66 | ALDH1A1 (0.56) | TP53MAPTTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275156-A1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | NEUPROTECT PTY LTD (AU) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275156-A1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | BAX, MAPKAPK2, MAPK6 | PDE4A 3285/4885PDE4B 2723/4885PDE4C 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.