Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16048625 | 0.75 | PDE4A (0.41) | CYP19A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8063014 | 0.71 | PDE4A (0.54) | CYP19A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17708872 | 0.69 | ALDH1A1 (0.46) | CYP19A1MAOBNPC1MAPTRAB9A | |
| SCHEMBL4358165 | 0.68 | AR (0.68) | CYP19A1ARMAOAMAOBPSMB5 | |
| SCHEMBL4370495 | 0.67 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DMAPT | |
| 3'-Hydroxyflavanone SCHEMBL5929195 | 0.65 | CYP19A1 (0.79) | CYP19A1ARMAOAMAOBPSMB5 | |
| 3'-Hydroxyflavanone SCHEMBL5088596 | 0.65 | CYP19A1 (0.79) | CYP19A1ARMAOAMAOBPSMB5 | |
| 3'-Hydroxyflavanone SCHEMBL15531909 | 0.65 | CYP19A1 (0.79) | CYP19A1ARMAOAMAOBPSMB5 | |
| 3'-Hydroxyflavanone SCHEMBL29606797 | 0.65 | CYP19A1 (0.79) | CYP19A1ARMAOAMAOBPSMB5 | |
| SCHEMBL6357776 | 0.64 | MRGPRX4 (0.53) | NPC1CYP3A4MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742033-B1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | ARMARON BIO PTY LTD (AU) | 2018-09-19 | — | — | EP | disclosed |
| US-20140275156-A1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | NEUPROTECT PTY LTD (AU) | 2014-09-18 | — | — | US | disclosed |
| EP-2742033-A1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | Neuprotect PTY Ltd (AU) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013020184-A1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | NEUPROTECT PTY LTD (AU) | 2013-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275156-A1 | FLAVONOID COMPOUNDS, AND METHODS OF USE THEREOF | BAX, MAPKAPK2, MAPK6 | CYP19A1 3123/4885PDE4A 3285/4885PDE4B 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.