Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16485511 | 0.86 | SMN1; SMN2 (0.47) | RETKDRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL17085406 | 0.81 | KDM4E (0.40) | SMN1; SMN2MAPTKDM4EHPGDLMNA | |
| SCHEMBL28320416 | 0.79 | ALDH1A1 (0.56) | MAPTKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL16048625 | 0.78 | PDE4A (0.41) | RETKDRMAPTLMNAALDH1A1 | |
| SCHEMBL25434717 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2MAPTKDM4EHPGDAGTR1 | |
| SCHEMBL30576367 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2MAPTKDM4EHPGDAGTR1 | |
| SCHEMBL25434723 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2MAPTKDM4EHPGDAGTR1 | |
| SCHEMBL7242379 | 0.76 | ALDH1A1 (0.57) | MAPTKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL10608985 | 0.75 | ALDH1A1 (0.67) | SMN1; SMN2MAPTKDM4EHPGDAGTR1 | |
| SCHEMBL21722487 | 0.75 | CYP2C9 (0.61) | MAPTKDM4EHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259373-A1 | NOVEL FLAVONOID COMPOUNDS AND USES THEREOF | ARMARON BIO PTY LTD (AU) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259373-A1 | NOVEL FLAVONOID COMPOUNDS AND USES THEREOF | BAX, CASP3, BAD | RET 3008/4885KDR 456/4885SMN1; SMN2 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.