Pentorex

Pentorex

SCHEMBL160519

CC(c1ccccc1)C(C)(C)N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.44
RIPK1 Q13546 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2C P18825 1/20 0.43
LMNA P02545 1/20 0.43
HIF1A Q16665 1/20 0.43
KDM4E B2RXH2 1/20 0.43
DPP4 P27487 2/20 0.42
F2 P00734 1/20 0.42
ALDH1A1 P00352 1/20 0.41
AOC3 Q16853 2/20 0.41
CACNA1F O60840 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
ADRA2B P18089 1/20 0.41
CHRM3 P20309 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
OPRK1 P41145 1/20 0.41
CACNA1D Q01668 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11968994 0.85 TAAR1 (0.44) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL3367523 0.81 ADRA2A (0.45) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL9768717 0.81 TAAR1 (0.41) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL14944876 0.79 CYP1A2 (0.42) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL14431333 0.79 TAAR1 (0.50) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL18470550 0.79 TAAR1 (0.50) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL416895 0.79 TAAR1 (0.50) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL20706326 0.78 CHRNA7 (0.39) LMNAALDH1A1SLC6A3
SCHEMBL29998966 0.78 TAAR1 (0.48) TAAR1RIPK1ADRA2AADRA2CLMNA
SCHEMBL20306752 0.77 RIPK1 (0.45) TAAR1RIPK1ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025136206-A1 A NASAL DEVICE FOR USE IN DRUG DELIVERY VIA THE NASAL CAVITY NOSEOPTION AB (SE) 2025-06-26 WO claimed
US-20200060997-A1 TARR Receptor Agonists for Sexual Dysfunction JOHN MCCOY 2020-02-27 US claimed
US-10463676-B2 Modified-release dosage forms of 5-HT2C agonists useful for weight management ARENA PHARMACEUTICALS, INC. (US) 2019-11-05 US claimed
US-20190292164-A1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2019-09-26 US claimed
US-20190275055-A1 Modified-Release Dosage Forms of 5-Ht2c Agonists Useful for Weight Management ARENA PHARMACEUTICALS, INC. 2019-09-12 US claimed
EP-3485878-A1 MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT Arena Pharmaceuticals, Inc. (US) 2019-05-22 EP claimed
EP-2611427-B1 MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT ARENA PHARM INC (US) 2018-10-17 EP claimed
EP-3366306-A2 USE OF SOME PEPTIDES IN DIAGNOSIS AND TREATMENT OF DIABETES, OBESITY AND METABOLIC DISEASES ASSOCIATED THERETO Istanbul Universitesi Rektorlugu (TR) 2018-08-29 EP claimed
EP-3351262-A1 CURAGLUTIDE FOR IN TREATMENT OF PREDIABETES, DIABETES, OBESITY AND METABOLIC DISEASES ASSOCIATED THERETO Istanbul Universitesi Rektorlugu (TR) 2018-07-25 EP claimed
CN-107669687-A 5 HT for body weight control2CThe modified release dosage form of activator 艾尼纳制药公司 2018-02-09 CN claimed
US-20030114495-A1 Substituted imidazoles as cannabinoid receptor modulators MERCK SHARP & DOHME CORP. 2003-06-19 US claimed
WO-2003045313-A2 2-AMINOQUINOLINE COMPOUNDS MERCK & CO. INC. (US) 2003-06-05 WO claimed
WO-2003045920-A1 4-AMINOQUINOLINE COMPOUNDS MERCK & CO., INC. (US) 2003-06-05 WO claimed
WO-2003007887-A2 SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS MERCK & CO., INC. (US) 2003-01-30 WO claimed
JP-2001524960-A 2001-12-04 JP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0977572-A1 USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING EATING DISORDERS MERCK SHARP & DOHME LTD. (GB) 2000-02-09 EP claimed
WO-1998047513-A1 USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING EATING DISORDERS MERCK SHARP & DOHME LIMITED (GB) 1998-10-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10463676-B2 Modified-release dosage forms of 5-HT2C agonists useful for weight management HTR2C, HTR2A, HTR3C TAAR1 180/4885RIPK1 3328/4885ADRA2A 34/4885
US-20030114495-A1 Substituted imidazoles as cannabinoid receptor modulators CNR1, CNR2, GPR119 TAAR1 74/4885RIPK1 448/4885ADRA2A 426/4885
US-20190275055-A1 Modified-Release Dosage Forms of 5-Ht2c Agonists Useful for Weight Management HTR2C, HTR2A, HTR3C TAAR1 180/4885RIPK1 3328/4885ADRA2A 34/4885
US-20190292164-A1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE GK, DGKI, DGKA TAAR1 1356/4885RIPK1 1880/4885ADRA2A 2902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.