Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14706783 | 0.83 | LMNA (0.52) | RECQLHTTMAPTLMNAALDH1A1 | |
| SCHEMBL14203994 | 0.76 | HTT (0.47) | HTTMAPTALDH1A1ADORA2ACNOT7 | |
| SCHEMBL17544854 | 0.74 | SIGMAR1 (0.44) | LMNAPOLBF2MAPK1 | |
| SCHEMBL5283248 | 0.73 | ALDH1A1 (0.40) | LMNAALDH1A1ADORA2AKMT2APOLB | |
| SCHEMBL5275734 | 0.72 | — | — | |
| SCHEMBL2056167 | 0.70 | ALDH1A1 (0.54) | RECQLMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL29238319 | 0.68 | HTR1A (0.42) | LMNAALDH1A1POLB | |
| SCHEMBL3264495 | 0.67 | CYP3A4 (0.45) | RECQLHTTKMT2APOLBATM | |
| SCHEMBL29987132 | 0.67 | MAPK1 (0.48) | HTTMAPTLMNAALDH1A1ADORA2A | |
| SCHEMBL10719904 | 0.67 | SIGMAR1 (0.44) | HTTLMNACNOT7POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835470-B2 | Mandelamide heterocyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-16 | — | — | US | disclosed |