Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063545 | 0.91 | GPR174 (0.33) | PPOXGPR174MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16063540 | 0.91 | GPR174 (0.33) | PPOXGPR174MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17466087 | 0.86 | PPOX (0.46) | PPOXMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16063494 | 0.85 | PPOX (0.41) | PPOXGPR174MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16063453 | 0.84 | GPR174 (0.33) | GPR174MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16063527 | 0.83 | KMT2A (0.36) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16063587 | 0.83 | KMT2A (0.36) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16063466 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL16063490 | 0.79 | KDM4E (0.40) | GPR174MAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16063512 | 0.79 | KDM4E (0.41) | GPR174MAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142308-A1 | BICYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | 公益財団法人相模中央化学研究所 (JP) | 2014-09-18 | — | — | WO | disclosed |