Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063527 | 1.00 | KMT2A (0.36) | KMT2AMAPTALDH1A1POLBNPC1 | |
| SCHEMBL16063545 | 0.92 | GPR174 (0.33) | KMT2AMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16063540 | 0.92 | GPR174 (0.33) | KMT2AMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16063565 | 0.85 | HTT (0.40) | KMT2AMAPTALDH1A1MAPK1LMNA | |
| SCHEMBL16063521 | 0.83 | ALDH1A1 (0.40) | KMT2AMAPTALDH1A1POLBNPC1 | |
| SCHEMBL16063497 | 0.83 | PPOX (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL16063453 | 0.83 | GPR174 (0.33) | KMT2AMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16063519 | 0.79 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL17466169 | 0.78 | MAPT (0.40) | MAPTALDH1A1POLBNPC1SMN1; SMN2 | |
| SCHEMBL16063523 | 0.78 | MAPT (0.42) | KMT2AMAPTALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142308-A1 | BICYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | 公益財団法人相模中央化学研究所 (JP) | 2014-09-18 | — | — | WO | disclosed |