Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063540 | 1.00 | GPR174 (0.33) | GPR174KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL16063587 | 0.92 | KMT2A (0.36) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16063527 | 0.92 | KMT2A (0.36) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16063497 | 0.91 | PPOX (0.41) | GPR174KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16063453 | 0.91 | GPR174 (0.33) | GPR174KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL16068811 | 0.85 | PPOX (0.42) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL16063466 | 0.84 | ALDH1A1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL16063490 | 0.83 | KDM4E (0.40) | GPR174KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL16063512 | 0.82 | KDM4E (0.41) | GPR174KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL16068820 | 0.80 | MAPT (0.33) | GPR174MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142308-A1 | BICYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | 公益財団法人相模中央化学研究所 (JP) | 2014-09-18 | — | — | WO | disclosed |