SCHEMBL1606368

SCHEMBL1606368

CCO[Si](CCCCN)(OCC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.37
TLR8 Q9NR97 4/20 0.33
HRH1 P35367 2/20 0.32
HTR2A P28223 1/20 0.32
SLC7A5 Q01650 1/20 0.32
KIF11 P52732 6/20 0.32
KCNH2 Q12809 1/20 0.31
TLR2 O60603 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1069349 0.95 MAOA (0.34) MAOATLR8HRH1HTR2ASLC7A5
SCHEMBL11681048 0.92 MAOA (0.33) MAOATLR8
SCHEMBL707984 0.91 LTA4H (0.32)
SCHEMBL6697042 0.87 KIF11 (0.34) HTR2AKIF11
SCHEMBL647736 0.87 TSHR (0.33)
SCHEMBL19470825 0.86 LTA4H (0.37) KCNH2
SCHEMBL19470880 0.84 KCNH2 (0.39) MAOAHRH1HTR2AKCNH2
SCHEMBL20483789 0.84 KCNH2 (0.39) MAOAHRH1HTR2AKCNH2
SCHEMBL19470865 0.84 KCNH2 (0.39) MAOAHRH1HTR2AKCNH2
SCHEMBL19470850 0.84 KCNH2 (0.39) MAOAHRH1HTR2AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2771379-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP Assets B.V. (NL) 2014-09-03 EP claimed
US-20140242399-A1 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2014-08-28 US claimed
WO-2013060767-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2013-05-02 WO claimed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
EP-0432748-B1 Glass fiber size OSI SPECIALTIES INC (US) 1998-02-25 EP claimed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US claimed
EP-0336533-B1 Process to enhance the tensile strength of reclaimed sand bonded with ester cured alkaline phenolic resin BORDEN INC (US) 1995-05-03 EP claimed
EP-0620255-A1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD. (KR) 1994-10-19 EP claimed
US-5190993-A Molds and foundry cores BORDEN, INC. (US) 1993-03-02 US claimed
US-5091465-A Silylated polyester UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-02-25 US claimed
EP-0139512-B1 SILANE ACETOACETARYLIDE DYES, COMPOSITE PIGMENTS OBTAINABLE THEREFROM, AND PROCESSES FOR PREPARING THE SAME Montedison S.p.A. (IT) 1987-09-09 EP claimed
EP-0140620-B1 SILANE ANTHRAQUINONE DYES, COMPOSITE PIGMENTS OBTAINABLE THEREFROM, AND PROCESSES FOR PREPARING THE SAME Montedison S.p.A. (IT) 1987-08-12 EP claimed
EP-0123577-B1 SILANIC PHTALOCYANINIC DYES AND COMPOSITE PIGMENTS Montedison S.p.A. (IT) 1987-06-03 EP claimed
EP-0103986-B1 ORGANIC ANTHRAQUINONE DYES CONTAINING SILANE GROUPS,PIGMENTS AND PROCESS FOR PREPARING THE SAME Montedison S.p.A. (IT) 1987-04-08 EP claimed
EP-0148022-A2 Silane quinacridone dyes, composite pigments obtainable therefrom, and processes for preparing the same Montedison S.p.A. (IT) 1985-07-10 EP claimed
EP-0140620-A1 Silane anthraquinone dyes, composite pigments obtainable therefrom, and processes for preparing the same Montedison S.p.A. (IT) 1985-05-08 EP claimed
EP-0140688-A2 Silane perylene dyes, composite pigments obtainable therefrom, and processes for preparing the same Montedison S.p.A. (IT) 1985-05-08 EP claimed
EP-0123577-A1 Silanic phtalocyaninic dyes and composite pigments Montedison S.p.A. (IT) 1984-10-31 EP claimed
US-4458073-A PLASTICS, PAINTS, FIBERS, INKS, PRINTING PASTES MONTEFLUOS S.P.A. (IT) 1984-07-03 US claimed
EP-0103986-A2 Organic anthraquinone dyes containing silane groups,pigments and process for preparing the same Montedison S.p.A. (IT) 1984-03-28 EP claimed