Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | RASGRP3 | Q8IV61 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686318 | 0.93 | TSHR (0.50) | TSHRAPOBEC3AAPOBEC3GCA1CA2 | |
| SCHEMBL14839401 | 0.91 | TSHR (0.47) | TSHRAPOBEC3AAPOBEC3GCA1CA2 | |
| SCHEMBL14839354 | 0.88 | TSHR (0.47) | TSHRCA1CA2ESR2PRKCA | |
| SCHEMBL19753230 | 0.88 | KMT2A (0.46) | TSHRAPOBEC3AAPOBEC3GPRKCAPRKCE | |
| SCHEMBL15799989 | 0.87 | ESR1 (0.54) | TSHRCA1CA2ESR2CYP2C19 | |
| SCHEMBL16119470 | 0.87 | MAPT (0.47) | TSHRCA1CA2ESR2POLB | |
| SCHEMBL12959101 | 0.87 | RAB9A (0.47) | TSHRCA1CA2ESR2PRKCA | |
| SCHEMBL17465564 | 0.86 | POLB (0.46) | TSHRCA1CA2ESR2POLB | |
| SCHEMBL9215046 | 0.86 | TSHR (0.45) | TSHRCA1CA2ESR2POLB | |
| SCHEMBL14491810 | 0.86 | TSHR (0.48) | TSHRAPOBEC3AAPOBEC3GCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542268-B2 | Cationically curable compositions with latent reducing agent demonstrating low cure temperature | HENKEL AG & CO. KGAA (DE) | 2023-01-03 | — | — | US | disclosed |
| US-20210107915-A1 | CATIONICALLY CURABLE COMPOSITIONS WITH LATENT REDUCING AGENT DEMONSTRATING LOW CURE TEMPERATURE | HENKEL AG & CO. KGAA (DE) | 2021-04-15 | — | — | US | disclosed |
| WO-2020006159-A1 | CATIONICALLY CURABLE COMPOSITIONS WITH LATENT REDUCING AGENT DEMONSTRATING LOW CURE TEMPERATURE | Henkel IP & Holding GmbH (DE) | 2020-01-02 | — | — | WO | disclosed |
| WO-2014152543-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-09-25 | — | — | WO | disclosed |
| US-20140264165-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542268-B2 | Cationically curable compositions with latent reducing agent demonstrating low cure temperature | CHIT1, SGMS2, LTA | TSHR 4804/4885APOBEC3A 1322/4885APOBEC3G 1252/4885 |
| US-20210107915-A1 | CATIONICALLY CURABLE COMPOSITIONS WITH LATENT REDUCING AGENT DEMONSTRATING LOW CURE TEMPERATURE | CHIT1, SGMS2, LTA | TSHR 4804/4885APOBEC3A 1322/4885APOBEC3G 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.